— Free checklist · for analytical chemists
The validation-readiness checklist
The five questions to answer in development, before validation asks them. The checks I run on every method, and what it costs to skip each.
What's inside
One page, five questions. Each with the checks to run in development and the one line of cost for skipping it.
- Specificity — what co-elutes under your peak
- Linearity and range — where QC actually runs
- Accuracy and precision — across analysts, days, and columns
- Robustness — pH, organic, and temperature drift
- Stability — what the analyte does before injection
The one that bites most is robustness. A method that only behaves on one system, at one temperature, is the one that fails on transfer.
From 14 years across pharma, CRO, environmental, and natural-product labs.
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